Topics Map > IRB Reliance & Collaborative Research > Partners

Greater Plains Cooperative (GPC) Reliance Fact Sheet

Version date: March 2015

What is the GPC?

The GPC is a network of ten medical centers focused on improving healthcare delivery through ongoing learning, adoption of evidence-based practices, and active research dissemination. The GPC has an IRB reliance agreement that has been finalized. This agreement allows for eligible studies involving one or more GPC institutions to be reviewed by a single IRB of record.

Which institutions are GPC partners?

Who may qualify to use the GPC reliance agreement?

Researchers affiliated with one or more GPC institutions may use the GPC reliance agreement.

What types of research may qualify for review under the GPC reliance agreement?

The GPC is funded by PCORI, which is focused on patient-centered outcomes research. The IRB reliance agreement, however, is not limited to a specific type of research and studies involving other than patient-centered outcomes research may qualify. Each GPC institution, however, reserves the right to retain local IRB oversight if deemed appropriate for a certain study.

What is the first step in requesting review under the GPC reliance agreement?

To be eligible to use the GPC reliance agreement, studies must first be reviewed and approved by the GPC governing body. The first step in the process is submitting study materials to GPC administration for review by the governing body. After approval, study materials are provided to IRB administrators at the participating institutions to determine whether review by a single IRB is appropriate. NOTE: Some GPC partner institutions will consider using the GPC reliance agreement for studies not formally designated as GPC studies. Please consult with the HS-IRBs’ Reliance Team for additional guidance.

How long does it take for GPC IRB reliance partners to determine whether a study qualifies for review by a single IRB?

IRB administrators typically review study materials promptly following approval by the GPC governing body. How quickly an IRB office can determine whether review by a single IRB is appropriate varies and depends on factors such as how well the study protocol is prepared and whether local institutional requirements (e.g., training, ancillary committee reviews, etc.) have been met.

  • Please contact the HS IRBs’ Reliance Team if you are interested in using the GPC reliance agreement.
  • When preparing a study for consideration by the GPC, please keep in mind that all GPC studies require a detailed study protocol as well as delegation of authority logs for each participating site.

Who can I contact with questions about the HS IRBs participation in the GPC?

Please email any questions to


A website with additional information about the GPC IRB reliance process is in development. The current main GPC website includes some basic information about the research partnership.

Keywords:reliance partner   Doc ID:48730
Owner:Monica E.Group:Health Sciences IRBs
Created:2015-03-12 13:38 CDTUpdated:2018-01-23 17:38 CDT
Sites:Health Sciences IRBs
Feedback:  0   0