Office 365 / WiscMail / WiscMail Plus - Dealing With Replies To Your Automated or Mass Email
This document explains recommended best practice for sending automated and mass email.
Don't use a no-reply from address. A common usage is to prevent users from replying to the messages. However, your users might have a legitimate reason to contact you, and you don't want to inconvenience them. You also may encounter delivery problems where you will need to see when messages bounce.
Send replies and bounces to a dedicated account. Create or request a new Office 365 Service Account. Use this new address as the from address when sending your messages.
Use a vacation message to instruct repliers. If you would like to provide instructions for users that reply to use the correct method of support, set a vacation message on this new account that explains how to contact you via the official support channel.
Filter messages that you don't intend to read. If you don't intend to read the messages, create a filter on the account to file all messages into the "Deleted Items" folder.
Look for bounced messages. If users complain that their messages aren't being received, check this account to see if the message bounced. Sometimes the account is over quota, or there were other delivery issues that can only be determined by looking at the information in the bounced message.
Use a Reply-to address. If you would like users to be able to reply to a different address (such as firstname.lastname@example.org) then set the Reply-to header to the address that you would like these replies to go to.