Central IRB Gateway

The Health Sciences Institutional Review Boards (HS IRBs) have contracted with independent IRBs, including Chesapeake, Schulman, Quorum, and WIRB (Western IRB).

The Reliance Team serves as UW-Madison research teams’ liaison between the HS IRBs Office and the independent IRBs. The Reliance Team can provide guidance regarding submission to an independent IRB; please see Contact Information for further assistance.

For studies ongoing and approved by WIRB as of February 17, 2018, please see the Legacy WIRB Studies page.

To cede a new study to an external, independent IRB of Record – including a new submission to WIRB – UW research teams must obtain institutional sign-off via the completion of a ceded review in the UW-Madison ARROW system. A ceded review application is a truncated ARROW application to document that a study is eligible to be ceded to an external, independent IRB per existing reliance agreements. Start with the initial review page for guidance on this process.

News and Announcements

1/25/18: Due in part to the recently announced delay in revisions to the Common Rule, the new ARROW submission process for independent IRBs, including WIRB, has been delayed until 2/17/18. For new studies using WIRB, please continue to use the current process (for checklists/forms, email submitwirb@medicine.wisc.edu) until 2/17/18. For other independent IRBs (e.g., Quorum Advarra), please contact centralirb@medicine.wisc.edu for assistance. Cede requests to all independent IRBs, including WIRB, may be submitted via ARROW beginning 2/17/18. The HS-IRBs Reliance Team will require the new ARROW process beginning 3/1/18.

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