Central IRB Gateway

The Health Sciences Institutional Review Boards (HS IRBs) have contracted with independent IRBs, including Chesapeake, Schulman, Quorum, and WIRB (Western IRB).

The Reliance Team serves as UW-Madison research teams’ liaison between the HS IRBs Office and the independent IRBs. The Reliance Team can provide guidance regarding submission to an independent IRB; please see Contact Information for further assistance.

For studies ongoing and approved by WIRB as of January 20, 2018, please see the Legacy WIRB Studies page.

To cede a new study to an external, independent IRB of Record – including a new submission to WIRB – UW research teams must obtain institutional sign-off via the completion of a ceded review in the UW-Madison ARROW system. A ceded review application is a truncated ARROW application to document that a study is eligible to be ceded to an external, independent IRB per existing reliance agreements. Start with the initial review page for guidance on this process.

News and Announcements


1/19/18: Due in part to the recently announced delay in revisions to the Common Rule, the new ARROW submission process for independent IRBs, including WIRB, has been temporarily delayed. For new studies using WIRB, please continue to use the current process (for checklists/forms, email submitwirb@medicine.wisc.edu). For other independent IRBs (e.g., Quorum Advarra), please contact centralirb@medicine.wisc.edu for assistance. The HS-IRBs Reliance Team will provide an update when we have a new implementation date for the new ARROW submission process.


Available Trainings

Date Time
TBD TBD